New research released ahead of print and published in the journal Archives of Toxicology indicates that Roundup, the most common formulation of the herbicide glyphosate, is not only more toxic than its constituent ingredients, but is capable of damaging DNA within a human cell line when diluted down to 450-fold lower concentrations than presently used in GMO agricultural applications. In the researchers’ own words, Roundup has “genotoxic effects after short exposure to concentrations that correspond to a 450-fold dilution of spraying used in agriculture.”
The chemical – glyphosate – is the highest selling herbicide in the world and has been identified as having a wide range of potential adverse health effects — largely minimized and/or under-reported — which include over two dozen diseases.
This new research sheds light on a fundamental problem associated with toxicological risk assessments of agrichemicals (and novel manmade chemicals in general), namely, these assessments do not take into account the reality of synergistic toxicologies, i.e. the amplification of harm associated with multiple chemical exposures occurring simultaneously. Moreover, toxicological risk assessments on novel chemicals are based on the concept of determining “an acceptable level of harm,” instead of protecting those who would be exposed to a chemical by implementing the precautionary principle, i.e. if there is reason to believe that a chemical could cause harm (determined by animal and in vitro studies) then they should be regulated as if they do cause harm to humans.
Glyphosate exposure is now ubiquitous due to the fact that 88,000 tons of it were used in US in 2007 alone, and likely billions of additional pounds globally. Accumulating evidence indicates it is resistant to biodegradation and now contaminates the air, rain and groundwater throughout the areas where it has been applied.